Estrogens and a number of estrogen-like molecules pose a serious threat to the environment and global public health. We designed an efficient system for detecting, quantifying and degrading various estrogen-like phenolic endocrine disrupting molecules. The project utilized microalgal-bacterial consortium that will worked in synergy for bioremediation. The microalga Chlamydomonas was  engineered to express and secrete a laccase from the white rot fungus while the bacterium expressed an estrogen-sensitive RNA Polymerase which drove the expression of a reporter and mediator to enhance laccase activity.

  Algae Bacterium Consortium - Image Credit: Anindita Puri, SNU


Dr. Rohini Garg and Dr. Richa Priyadarshini
Shiv Nadar University, India