Tumor response to chemotherapy is often transient and short-lived because of the emergence of drug resistance. Adaptive therapy is a therapeutic regimen based on an evolutionary understanding of the tumor microenvironment. The approach is aimed to control the populations of sensitive and resistant cells in the tumor instead of relying on the maximum tolerated dose.

Adaptive Therapy Ranjini
                                        Principle of Adaptive Therapy

Currently, we are working on building models for intermittent androgen therapy based on prostrate cancer clinical data.

 

PI
Dr. Mohit Kumar Jolly
Place
Indian Institute of Science
Project Duration
Sept 2020 Onwards